AMERICAN BOARD OF INFECTIOUS DISEASES
CLINICAL PHARMACY
Domain 1: Patient Care and Therapeutics (about 50% of the exam):
- Pathophysiology and epidemiology of infections including: Bone and joint infections - Cardiovascular infections - Central nervous system infections - Gastrointestinal infections - HIV-infection and AIDS (including opportunistic infections) - Infections of reproductive organs - Intra-abdominal infections - Lower respiratory tract infections - Ophthalmologic infections - Sepsis - Sexually transmitted diseases - Skin and soft tissue infections - Tuberculosis and other mycobacterial infections - Upper respiratory tract infections - Urinary tract infections -Viral hepatitis
- Pharmacotherapies related to specific infectious diseases (e.g., bacterial, fungal, viral)
- Pharmacokinetics and pharmacodynamics of antimicrobials (e.g. antifungals)
- Pharmacology of antimicrobials
- Pharmacology of vaccines
- Pharmacology of biological response modifiers (e.g., TNF inhibitors, colony-stimulating factors) Mechanisms of pathogen resistance
- Antimicrobial drug interactions
- Complications of antimicrobials
- Complications of vaccines
- Spectrum of activity of antimicrobials
- Structure and characteristics of pathogenic microorganisms
- Basic microbiology laboratory procedures
- Clinical laboratory tests in ID (e.g., rapid diagnostic testing, RPR, antibody concentrations)
- Diagnostic and therapeutic procedures in ID (e.g., lumbar puncture, paracentesis)
- Factors that alter the risk of infection
- Immunologic response to infection
- Immunologic therapy (e.g., immunoglobulin, Mannose Binding Lectin)
- Outpatient parenteral antimicrobial therapy
- Therapeutic monitoring of antimicrobials
- Factors that may impact response to therapy (e.g., dose optimization, penetration of antimicrobials, source control, immune status)
- Antimicrobial de-escalation
- Measures to monitor response to antimicrobial therapy (e.g., resolution of signs and symptoms, laboratory data, readmission, development of drug resistance)
- Patient and caregiver education and counseling techniques
- Antimicrobial allergy and cross-reactivity
- Antimicrobial desensitization
- Preventive therapies (e.g., infection prophylaxis, vaccines, behavior modification)
- Factors to consider when differentiating infection from non-infection
- Considerations in special populations (e.g., geriatrics, pediatrics, obesity)
- Facilitation across transitions of care
- Considerations in drug delivery
Domain 2: Education, Research and Scholarship (about 20% of the exam):
- Principles and methods of educating, training and mentoring pharmacists, pharmacy students, residents, and fellows.
- Principles and methods of educating and communicating with other healthcare professionals
- Appropriate resources for infectious disease information
- Research study design and methodology, including those specific to ID (e.g., Monte Carlo simulation, microbiologic surveillance, time-kill)
- Statistical methods
- Clinical application and limitations of published data and reports
- Regulatory and ethical issues related to conducting research
- Venues and processes for disseminating knowledge (e.g., audience-specific medical writing, publication, presentation)
- Mechanisms for continuing professional development in ID pharmacy
Domain 3: Antimicrobial Stewardship and Practice Management (about 25% of the exam):
- Antibiogram design and development
- Antimicrobial stewardship strategies
- Antimicrobial resistance trends
- Metrics for antimicrobial use
- Clinical practice guidelines for ID (e.g., IDSA, SHEA, CDC)
- Methods for developing and evaluating clinical practice guidelines
- Infection control and prevention strategies
- Metrics for infection control
- National accreditation and regulatory organizations and requirements (e.g., Joint Commission, CMS, NHSN)
- Quality improvement strategies (e.g., MUE, FMEA, root cause analysis)
- Roles of infection control and prevention, microbiology and ID divisions/departments
- Collaboration strategies and consensus building
- Metrics for evaluating value of ID pharmacy services
- Pharmacoeconomic assessment of antimicrobials
Domain 4: Public Health and Advocacy (about 5% of the exam)
- Public health information resources related to infectious diseases
- Public health services related to infectious diseases
- CDC notifiable infectious diseases
- Populations at risk for infection
- ACIP immunization recommendations and schedules
- Strategies for advocating vaccination and prudent antimicrobial use
- Professional organizations and their roles and resources related to patient advocacy (e.g., Immunization Action Coalition, IDSA, ASHP, APhA, SIDP)
- Screening guidelines for infectious diseases (e.g. HIV, STDs, tuberculosis)
- Agents that have the potential to become epidemic or pandemic
- Emerging infectious diseases
- History of vaccine-preventable diseases
Reserve the course